My laboratory uses a functional genomic approach to study human disease processes ranging from inflammation to neoplasia. Currently we are focused on using DNA and protein microarrays to molecularly dissect prostate cancer. We hope to define a molecular classification for this common disease that will be of use in clinical practice. Hypotheses generated from our global profiling studies have fueled our current research endeavors leading to the identification of several candidate biomarkers and novel cancer regulatory genes. Furthermore, we are developing bioinformatic techniques and resources that will be useful in analyzing gene and proteomic expression data in the context of clinical parameters.